Alcohols and polyols
- (1)
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- (350)
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- (1)
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- (155)
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- (30)
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- (20)
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- (10)
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- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
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- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (114)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
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- (7)
- (14)
- (2)
- (1)
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- (1)
- (1)
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- (21)
- (5)
- (2)
- (2)
- (1)
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- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
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- (1)
- (20)
- (10)
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- (15)
- (1)
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- (6)
- (2)
- (1)
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- (2)
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- (1)
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- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (14)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (14)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
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- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (5)
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- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
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- (3)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
- (10)
- (1)
- (1)
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- (11)
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- (20)
- (21)
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- (8)
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- (1)
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- (2)
- (1)
- (1)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
- (4)
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- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
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- (1)
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- (1)
- (10)
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- (1)
- (9)
- (1)
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- (4)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (9)
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- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (81)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
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- (16)
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- (21)
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- (1)
- (67)
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- (7)
- (4)
- (86)
- (1)
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- (72)
- (3)
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- (238)
- (4)
- (2)
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- (21)
- (281)
- (17)
- (1)
- (6)
- (279)
- (28)
- (2)
- (25)
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- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (731)
- (11)
- (3)
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- (9)
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- (66)
- (2)
- (2)
- (18)
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- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
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- (3)
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- (6)
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Medchemexpress LLC Cct241533 hydrochloride | 1431697-96-9 | 98.55% | 478.94 | 50 MG
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CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC50 of 3 nM and a Ki of 1.16 nM. It exhibits minimal cross-reactivity against a panel of kinases at 1 μM. X-ray crystallography confirms its binding to CHK2 in the ATP pocket. The compound blocks CHK2 activity in human tumor cell lines in response to DNA damage, significantly enhancing the cytotoxicity of two structurally distinct PARP inhibitors. Clear induction of the pS516 CHK2 signal by PARP inhibitor alone is abolished by CCT241533. The cytotoxicity (GI50) in HT-29, HeLa, and MCF-7 cells is 1.7, 2.2, and 5.1 μM, respectively.
- Potent and selective CHK2 inhibitor (IC50=3 nM)
- 63-fold selectivity over CHK1 (IC50=190 nM)
- Low hERG inhibition (IC50=22 μM)
- Blocks CHK2 activity in human tumor cell lines in response to DNA damage
- Enhances cytotoxicity of PARP inhibitors
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Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 100 MG
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GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor and can be used for cancer study.
- Functions as a cysteine cathepsin inhibitor
- Suitable for cancer research
- Chemical formula C33H40ClN3O6
- Appears as a solid, white to off-white powder
- Soluble in DMSO at 125 mg/mL (in vitro)
- Soluble in 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline at 5 mg/mL (in vivo)
- Classified under metabolic enzyme/protease and cathepsin
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Medchemexpress LLC Cl-amidine (hydrochloride) | 1373232-26-8 | 99.8% | 347.24 | C14H20Cl2N4O2 | 5 MG
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Cl-amidine (hydrochloride) is a high-purity small-molecule inhibitor of peptidylarginine deiminases (PADs), used in biochemical and cellular research to block protein citrullination and probe PAD-mediated pathways.
- Potent inhibition of PAD enzymes, including PAD1, PAD3, and PAD4.
- High chemical purity suitable for biochemical assays.
- Solid form enables flexible preparation of solutions.
- Stable when stored at recommended low temperatures.
- Available in milligram quantities for research use.
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Medchemexpress LLC Ninhydrin | 485-47-2 | 99.97% | 25 G
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Ninhydrin is a chromogenic analytical probe used for the quantification of amino acids and proteins. It reacts with primary and secondary amines, producing a characteristic blue or purple reaction product: diketohydrindylidene-diketohydrindamine. Most amino acids, with the exception of proline, can be hydrolyzed and subsequently quantified colorimetrically following chromatographic separation. This product, appearing as a white to light yellow solid, is intended for research use only and has not been fully validated for medical applications.
- Chromogenic analytical probe for the quantification of amino acids and proteins.
- Reacts with primary and secondary amines.
- Produces a blue or purple reaction product.
- Suitable for the colorimetric quantification of most amino acids after chromatographic separation.
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Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 1 ML
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Ansofaxine hydrochloride (LY03005) is a triple reuptake inhibitor that targets serotonin, dopamine, and norepinephrine. It is intended for research use only.
- Inhibits serotonin reuptake (IC50: 723 nM)
- Inhibits dopamine reuptake (IC50: 491 nM)
- Inhibits norepinephrine reuptake (IC50: 763 nM)
- Purity of 99.44%
- Molecular weight of 417.97
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Medchemexpress LLC Zenidolol hydrochloride | 72795-01-8 | 99.7% | 313.86 | 100 MG
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Zenidolol hydrochloride (ICI-118551) is a highly selective β2 adrenergic receptor antagonist, demonstrating potent inhibition with Kis of 0.7, 49.5, and 611 nM for β2, β1, and β3 receptors, respectively. It is for research use only.
- Highly selective β2 adrenergic receptor antagonist
- Inhibits cAMP accumulation with an IC50 of 1.7 μM in IMCD cells
- Induces prominent vasorelaxation of norepinephrine (NE)-precontracted PA but not AO (at 10 μM)
- Has significant effects on beat duration in failing human heart, reducing time-to-peak contraction and time-to-90% relaxation compared with basal contraction
- Negative inotropic effect is not cAMP-related
- Overexpression of β2AR in rabbit myocytes enhances negative inotropic effects
- Reduces systolic pressure in the pulmonary circuit but not systemic arterial pressure when injected into the jugular vein of mice (at 0.2 mg/kg)
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Medchemexpress LLC Pociredir (hydrochloride) | 2490676-19-0 | 99.9% | 439.87 | 25 MG
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Pociredir (FTX-6058) hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). It can induce HbF protein expression in cell and murine models and is used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia.
- Inhibits PRC2 via binding to EED
- Induces robust HbF protein expression in cell and murine models
- Used for research of select hemoglobinopathies
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Medchemexpress LLC Befiradol hydrochloride | 2436760-81-3 | 99.9% | 430.32 | 100 MG
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Befiradol hydrochloride | 2436760-81-3 | 99.9% | 430.32 | 100 MG
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Medchemexpress LLC Almorexant hydrochlo 100mg | 913358-93-7 | 100MG
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Almorexant (ACT 078573) hydrochloride is an orally active potent and competitive dual orexin receptor antagonist with Kd values of 1 3 nM (OX1) and 0 17 nM (OX2) respectively Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides Almorexant hydrochloride totally blocked the intracellular Ca2 signal pathway Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis[1 [2 [3 [4
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Medchemexpress LLC Aplaviroc hydrochloride | 461023-63-2 | 99.9% | 614.17 | 100 MG
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Aplaviroc hydrochloride is a potent CCR5 antagonist, effective against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM. It also suppresses the infectivity and replication of HIV-1MDR variants at low concentrations. This compound binds to CCR5 with high affinity and has been shown to suppress R5 HIV-1 viremia in animal models. Aplaviroc hydrochloride has been involved in multiple clinical trials for HIV infection.
- Potent CCR5 antagonist
- Effective against wild-type R5 HIV-1 strains
- Suppresses HIV-1MDR variants
- Binds to CCR5 with high affinity
- Suppresses R5 HIV-1 viremia in animal models
- Investigated in clinical trials for HIV infection
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Medchemexpress LLC Amrubicin hydrochloride | 110311-30-3 | MFCD00876391 | 98.78% | C25H26ClNO9 | 1 MG
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Amrubicin hydrochloride (SM-5887) is a DNA topoisomerase II inhibitor primarily used for cancer research. It exhibits significant cytotoxic effects on various cell lines, including A549, HT-29, and K562 cells, and shows potent antitumor activities in SCLC tumors and other cancer xenograft models.
- DNA topoisomerase II inhibitor
- Used for cancer research
- Cytotoxic against A549, HT-29, and K562 cells
- Shows radio-enhancement effects on human lung adenocarcinoma A549 cells
- Antitumor activities against SCLC tumors
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Medchemexpress LLC Amiloride hydrochloride | 2016-88-8 | 99.8% | 25 MG
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Amiloride hydrochloride is an analytical standard intended for research and analytical applications. It acts as an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA), and is also identified as a blocker of the polycystin-2 (PC2; TRPP2) channel. This compound is commonly used as a reference standard in qualitative, quantitative, and methodological research experiments.
- Used as an analytical standard
- Inhibits epithelial sodium channel (ENaC)
- Inhibits urokinase-type plasminogen activator receptor (uTPA)
- Blocks polycystin-2 (PC2; TRPP2) channel
- Suitable for HPLC, GC, and MS experiments
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Medchemexpress LLC Enerisant hydrochloride | 1152749-07-9 | 95.0% | 10 MG
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Enerisant hydrochloride is the hydrochloride salt of a potent, selective histamine H3 receptor antagonist/inverse agonist supplied as a research reagent for preclinical and in vitro studies. It is provided as a solid for laboratory use and is not intended for human or veterinary applications.
- Potent histamine H3 receptor antagonist/inverse agonist.
- Hydrochloride salt form for improved stability and solubility.
- CAS number 1152749-07-9 and molecular formula C22H31ClN4O3.
- Molecular weight 434.96 g·mol-1.
- Typical purity 95.0%.
- Packaged as a 10 mg solid; store frozen per supplier guidance.
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Medchemexpress LLC Slm6031434 hydrochloride | 1897379-34-8 | 99.1% | 5MG
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Slm6031434 hydrochloride | 1897379-34-8 | 99.1% | 5MG
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Medchemexpress LLC Amotosalen hydrochloride | 161262-45-9 | MFCD09970539 | 99.9% | 337.8 g/mol | C17H20ClNO4 | 1 ML
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Amotosalen hydrochloride is a light-activated psoralen compound that crosslinks DNA and RNA upon UVA exposure, used for pathogen inactivation studies and for research applications requiring covalent nucleic acid modification. Supplied as a 10 mM solution (1 mL) with high purity and documented handling information, it is intended for laboratory research use under appropriate safety protocols.
- Photoactivated crosslinking of DNA and RNA for pathogen inactivation studies.
- Supplied as a ready-to-use 10 mM solution for consistent dosing.
- High purity suitable for analytical and biological research applications.
- Well-characterized molecular properties for reproducible results.
- Includes SDS and datasheet documentation for safe handling and use.
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